Brief Report: The Dopamine-3-Receptor Gene (DRD3) is Associated with Specific Repetitive Behavior in Autism Spectrum Disorder (ASD)
نویسندگان
چکیده
Recently the DRD3 gene has been associated with ASD in two independent samples. Follow up analysis of the risk allele of the SNP rs167771 in 91 subjects revealed a significant association with a specific type of repetitive behavior: the factor "insistence on sameness" (IS) derived from the Autism Diagnostic Interview. This risk allele was associated with a decreased risk for IS, but not with any other symptomatology. Further study and replication of this finding is necessary, bearing in mind that these results would not be statistically significant if corrected for multiple testing.
منابع مشابه
Evaluation of Intervention Programs for Children with Autism
The present study reviewed the literature about intervention programs for Autism Spectrum Disorder (ASD) among children. ASD is a long-term neurodevelopment disorder that is identified as impairment in the context of social communication and interaction, and the predominance of restricted and repetitive patterns of behavior, interests or activities. Intervention programs have objectives such as...
متن کاملNutritional and Dietary Interventions of Autistic Spectrum Disorders: A Short Review
Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous etiology, categorized by social communication deficits, repetitive or restrictive behaviors and interests. Epidemiological studies display that the incidence of autism is increasing, and the treatment of autism is vitally important. There...
متن کاملComparison of Motor Skills in At-risk with Autism Spectrum Disorder Children with Autism Spectrum Disorder and Typical Development Children
Background: Autism Spectrum Disorder (ASD) is a complex developmental disorder characterized by repetitive and stereotypical patterns, and difficulties with social communication and interaction in early childhood. Motor development and dysfunction in children with ASD has been the subject of study in recent years and has attracted much of the attention of researchers. As motor dysfunctions can ...
متن کاملThe comparing reading strategies and executive functions between successful and non successful students with autism spectrum disorder in education
Autism spectrum disorder is characterized by deficits in social communication and social intraction, and restricted and repetitive behvaiors, interest and activites. The purpose of this research is the comparing reading strategies and executive functions between successful and non successful students with autism spectrum disorder in education. The research population includes all students with ...
متن کاملRelationship Between Executive Functions and Pragmatic Language in Children With Autism Spectrum Disorders
Objectives: Children with Autism Spectrum Disorder (ASD) have problems in communicating and social interaction skills. Moreover, deficits in pragmatic language and executive functions are among the most important causes of communication and social interaction problems in this group. The present study aimed to determine the relationship between executive functioning and two of its indices (behav...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 42 شماره
صفحات -
تاریخ انتشار 2012